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Licensing agreement for maytansinoid Targeted Antibody Payload (TAP) technology

Companies: Abgenix
Amgen
ImmunoGen
Announcement date: Sep 16 2009
Related contracts: Collaborative R&D and licensing agreement for TAP prodrug technology for Xenomouse antigens
Licensing agreement for maytansinoid Targeted Antibody Payload (TAP) technology
Licensing agreement for TAP technology

Details

Announcement date: Sep 16 2009
Industry sectors: Bigpharma
Bigbiotech
Pharmaceutical
Biotech
Therapy areas: Oncology » Solid tumors
Technology types: Antibodies
Biological compounds
Discovery tools
Deal components: Licensing
Stages of development: Discovery
Preclinical
Geographic focus: Worldwide

Financials

Termsheet

Licensed the exclusive right to use the Company’s maytansinoid Targeted Antibody Payload (TAP) technology to develop anticancer therapeutics to an undisclosed target found on solid tumors.

Press Release

ImmunoGen Announces Amgen has Licensed Rights to Use the Company's TAP Technology for a Solid Tumor Target

WALTHAM, Mass.--(BUSINESS WIRE)--Sep. 16, 2009-- ImmunoGen, Inc. (Nasdaq: IMGN), a biotechnology company that develops targeted anticancer products, today announced that Amgen Inc. has licensed the exclusive right to use the Company’s maytansinoid Targeted Antibody Payload (TAP) technology to develop anticancer therapeutics to an undisclosed target found on solid tumors.

Daniel Junius, President and Chief Executive Officer, commented, “Amgen has an established track record of success in oncology and an expanding presence in antibody-based therapeutics. Amgen’s interest in antibody-drug conjugates is good for the field, and we’re pleased they’ve chosen to move forward with ImmunoGen’s technology.”

This license was taken under an agreement established in 2000 between ImmunoGen and Abgenix, Inc., which later was acquired by Amgen. Under the terms of the license, ImmunoGen receives a $1 million license payment upfront. The Company also is entitled to receive milestone payments potentially totaling $34 million plus royalties on the sales of any resulting products. Amgen is responsible for the development, manufacturing, and marketing of any products resulting from this license.

The agreement established in September 2000 grants Amgen certain rights to test ImmunoGen’s maytansinoid TAP technology with antibodies to specific targets and to license – on agreed-upon terms – the right to use the technology with antibodies to these targets to develop products.

About ImmunoGen, Inc.

ImmunoGen, Inc. develops targeted anticancer therapeutics using its expertise in cancer biology, monoclonal antibodies and the creation and attachment of potent cell-killing agents. The Company’s TAP technology uses antibodies to deliver one of ImmunoGen’s proprietary cell-killing agents specifically to cancer targets. In addition to the Company’s product pipeline, compounds utilizing the TAP technology are in clinical testing through ImmunoGen’s collaborations with Genentech (a wholly-owned member of the Roche Group), sanofi-aventis, Biogen Idec and Biotest. The most advanced compound, trastuzumab-DM1 (T-DM1), is in Phase III testing being conducted by Genentech and Roche. Other ImmunoGen collaborative partners include Bayer HealthCare and Amgen.

Filing Data

Not available.

Contract

Not available.